Xeljanz Side Effects

Image taken from http://www.niams.nih.gov/hi/t...

Image taken from http://www.niams.nih.gov/hi/topics/arthritis/rahandout.htm he:תמונה:Rheumatoid arthritis joint.heb.GIF (Photo credit: Wikipedia)

Xeljanz: Is this Treatment for Rheumatoid Arthritis Really Worth It?

Rheumatoid arthritis is an illness that can affect all parts of the body. However, it is mainly characterized by severe joint inflammation. This may later spread to the eyes, lungs and tissues. RA is systemic illness that attacks the immune system of the body which causes inflammation and severe pain. It is prevalent more in women than men between the ages of 40-60 years old. This does not mean that males should not take necessary precautions to keep this disease at bay. Even children have been known to be affected by rheumatoid arthritis.

Over 1.7 million Americans suffer from this condition. And over 30 million have succumbed to this illness worldwide, according to the Center of Disease Control and Prevention. There are treatments available for RA. However, studies show that patients  do not fully recover from the treatment that is administered.

Xeljanz is a recent and effective treatment option for people suffering from RA who have a poor response rate to other forms of treatment. The product was endorsed in November 2012 by the FDA and is taken 2 times daily. The drug was certified for use after 7 clinical trials showed that patients recorded improved physical mobility after it was administered.

The side effects for this drug include headaches, respiratory problems, fever, dark urine and a host of infections. Tofacitinib is an active ingredient in Xeljanz which triggers stomach pain, swelling of the face, lips, tongues and throat. It is also responsible for body aches, chest pains, painful urination, shortness of breath, mucus coughs, skin discoloration and loss of appetite.

Xeljanz has no record for harming unborn babies. However, pregnant women who use this drug need to be monitored around the clock. They should desist from using the drug if they notice any unusual happenings in their bodies. Xeljanz can lead to plenty of opportunistic infections because there is a breakdown of the immune system including cancers, lymphoma and tubercolosis.

This drug also increases liver enzyme trials, cholesterol and reduces the volume of blood count. Xeljanz was certified alongside a Risk Evaluation and Mitigation Strategy (REMS). And what this means is that the drug comes with a medication guide espousing critical pointers and safety precautions for patients as well as information about the healthcare providers available in case the side effects spiral out of control or taken a turn for the worse.

Xeljanz is manufactured by Pfizer, a pharmaceutical company that has continually improved the health and overall well-being of humans by confronting and challenging all diseases known to man. This product from Pfizer is the most effective treatment available for RA. Despite the overwhelming side-effects that come with it.

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Belviq Side Effects

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English: Logo of the . (Photo credit: Wikipedia)

Belviq: The FDA Approved Diet Drug With Tons of Side Effects

Belviq is the first prescription diet drug to be approved by the Food and Drug Administration in over 13 years. This diet pill controls appetites by stimulating the receptors of the brain towards secreting serotonin, a neurotransmitter that elicits feelings of satisfaction so that there is no willingness to eat food. The drug is manufactured by Arena Pharmaceuticals. Belviq was a weight loss drug created to help Americans wage war against obesity. Statistics show that 1 in every 3 Americans is overweight.

Users of the drug have said that the efficacy of the drug is in serious doubt. According to a clinical trial, only 47% of people who used the drug reported a loss of over 5% of their total body weight in a year. To put this in perspective, what this means is that a person who weighs 200 pounds will only lose 7 pounds in 365 days.

However, there is another school of thought, where users of the drug are told to complement it with a healthy diet and exercise regime. Furthermore, they are told to desist from usage if they fail to lose at least 5% of their body weight in 12 weeks. The argument is that treatment over a longer duration will not lead to any substantial weight loss. In other words, the drug does not work for everybody.

Despite the mixed reactions over the effectiveness of the Belviq drug. It is the symptoms that are major drawbacks. The prominent side effects of Belviq include dizziness, constipation, nausea and tiredness. Patients with diabetes might experience additional side effects like back pain, low blood sugar, cough and heart-related complications. A similar diet drug known as fenfluramine was taken off the market because of these symptoms.

Recently, FDA rejected the approval of Belviq for public use because of the heart problems, breast tumor development and increase brain functions that were associated with the drug. The pharmaceutical company refused to modify the drug. They only submitted research papers that showed that Belviq was not a risk factor if it was taken in little doses.

But even that poses a huge risk in itself. Belviq is highly addictive as people think that taking sizable doses in the absence of a healthy diet or working out hastens the weight loss process. It is surprising that the FDA has vetoed the use of this drug. Despite the health concerns this diet drug poses to people.

Belviq is not the only drug that has been certified by the FDA. Qnexa has also been recommended for approval even though documentation shows that it causes heart problems and birth deformities. Alli is another diet pill up for review, even though the side effects include oily excreta, vitamin deficiencies and potential liver damage.

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Lorcaserin side effects

Structure of the 5-HT2C receptor agonist lorca...

Structure of the 5-HT2C receptor agonist lorcaserin (Photo credit: Wikipedia)

Lorcaserin is a drug designed to help weight loss for those suffering from obesity .The drug was manufactured by the Arena Pharmaceutical .It was in the year 2010 the FDA voted against the drug .The unanimous decision was taken while keeping in mind the efficacy and safety of the drug. Finally during the month of October FDA announced that they cannot approve the drug because of the presence of lorcaserin .In spite of repeated warning there were individuals who started using the drug. It was a matter of time when they realized the ill effects of the drug. The drug is extremely harmful for human body and is strictly forbidden for pregnant. Some of the reported side effects are.

 

  • Cardiovascular conditions like peripheral edema (by 4.8%) and hypertension (by 5%)is a common side effect of this drug.
  • The common Genitourinary condition related to this drug is severe UTI( urinary tract infection) as high as 9 %.
  • Some of the common gastrointestinal side effects are vomiting and nausea feeling ( by 9.5%), dry mouth(by6%), toothache(by 3%), decreased appetite(by 3%),gastroenteritis(by 3 %), constipation(by 6%)
  • The drug is also known to have Hypersensitivity condition like severe seasonal allergy (by 3%)
  • Some of the common immunologic conditions of this drug are high level of prolactin .The excess level of prolactin can cause gynaecomastia ( in men) and galactorrhea.
  • The drug is known to have hypersensitivity conditions like rashes  and allergy on the upper epidermis.
  • Some of the common metabolic condition is known to occur with patients suffering from diabetes mellitus are hypoglycemia (by 30%) and deteriorating diabetes mellitus (by 3%)
  • Some of the common Hematologic condition are less WBC and RBC.These are serious conditions and can lead to numerous complications like neutropenia, leucopenia, anemia, lymphopenia, hematocrit and less hemoglobin.
  • The drug is known to have numerous Musculoskeletal like severe back ache (by12%), muscle spasm (by 5%), musculoskeletal pain (by 2.5%).
  • The drug is known to effect the nervous system of patients consuming the drug for prolong period of time. Some of the common side effects are headache (by7%), dizziness (by 7.5%) and fatigue (by8%).
  • The drug is known to have an adverse Psychiatric effect like insomnia (by 4 %), anxiety (by 4%), stress (by 3 %), cognitive impairment (by3 %) and DEPRESSION (by 3 %).
  • The drug is known to have negative effects on our respiratory system. Some of the common respiratory conditions are %) or pharyngeal pain (by 4 %), cough(by 8 %),RTI ( by 14 %), nasopharyngitis (by 12 %).
  • Some of the commonly reported ocular conditions are dry eye, blurred vision, conjunctiva infections, inflammations, cataract conditions, ocular sensation disorders, irritations, visual disorders etc.
  • Some other commonly related side effects are :
  • Suicidal tendency.
  • Hallucination.
  • Increased heart beat.
  • Fainting.
  • Swelling of limbs.
  • Nipple discharge and swelling of breast.
  • Erection of penis up to 4 hrs.
  • High Fever.
  • Sweating, tremor, uneven heart rate.
  • Flu, sore throat and mouth.
  • Mood swing.
  • Sudden decrease of blood sugar leading to hunger, confusion, dizziness, headache, sweating etc.
  • Finally the drug is completely for bidden for ladies who breast are feeding their kids since till date it has not been confirmed whether the drug is safe for just born kids.
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Qsymia side effects

phentermine

phentermine (Photo credit: Wikipedia)

Qsmya is a new drug for treating patients with obesity .The drug is approved by the FDA; US.The drug was launched in the year 2012 in July. Qsymia formerly known as the Qnexa is a combination of topiramate extended, phentermine, amine anorectic, and phentermine. Initially the drug became popular among individuals willing to get rid of obesity. Initially the drug was prescribed by registered physician of the state. The dosages are determined according to the BMI of the patient. However within few months numerous instances were reported where in the patient consuming this drug suffered from numerous side effects. The two key ingredients of Qsymia: Phentermine and topiramate was reportedly the culprit behind these side effects. For many reasons these two molecules was not friendly with many patients.

The Phentermine is not safe for many individual suffering from obesity. Several tests and reports have forced the medical world to agree that this particular molecule is a potential risk for human wellbeing. Some of the frequently reported side effects of this molecule are discussed below:

  • Gastrointestinal: the molecule is often responsible for diarrhea, unpleasant taste in mouth, constipation and dryness in throat and mouth.
  • Endocrine: the molecule is responsible for impotent condition and alters the libido in individual consuming drugs containing this molecule.
  • The common Dermatologic condition reported due to the intake of this molecule is the allergies reaction called urticaria.
  • Some of the Cardiovascular condition related to this molecule are ischemic,palpitation,high blood pressure, tachycardia .Many patients have been admitted with primary valvular heart issues ad pulmonary hypertension .Numerous records also reveals that this molecule is responsible for ventricular fabrication., ischemic cerebrovascular, cerebral infarctSome other related side effect are :
  • Swelling of ankles and feet.
  • Mood swing.
  • Insomnia.
  • Dizziness and headache.
  • Lack of breath.

The Topiramate another key molecule of the drug is equally dangerous for human health. Some of the reported side effects are:

  • Some of the common renal conditions are renal tubular acidosis and kidney stone.
  • The cardiovascular side effects include sudden palpitation, hypertension, hypotension and uneasiness while breathing.
  • The immunologic conditions like genital moniliasis and infection are commonly reported by patients consuming these molecules).
  • The hepatic condition includes hepatitis and hepatic failure (fatal in certain case).
  • The commonly observed hypersensitivity conditions include rashes and allergy.

The nervous system is probably the major area that suffers from the side effects of this molecule ataxia, dizziness, speech disorders, vertigo, paresthesias, tinnitus, nystagmus, hypokinesia, grand mal seizures and psychomotor slowing.

The commonly reported gastrointestinal problems are gastroenteritis, vomiting, tooth disorder, flatulence, diarrhea, constipation, gastro esophageal reflux and tongue edema

Some of the Musculoskeletal conditions are myalgia, hemi paresis, muscle weakness, arthralgia etc.

Some other side effects are :

  • Loss of vision.
  • Dizziness.
  • Weight loss.
  • Sore throat and stuffy nose.
  • Pin behind and around eyes
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Slim Quick Side Effects

Body mass index. Graphics is made language ind...

Body mass index. Graphics is made language independent. (Photo credit: Wikipedia)

The Slim quick is a diet supplementary pill especially designed for a specific group of society. The Pill is used by women to reduce weight .The basic ingredient of Slim Quick assists users to repress the desire to crave for more food. The pill has to be consumed with some exercise regime and diet .The Slim Quick manufacturer house claims the formula enhances the metabolic rate or energy of our body thus reducing our appetite to a considerable amount .The company claims to have numerous scientific substantiation that hormonal and physiological process related to the weight process varies between genders .Thus this particular drug is exclusively designed for females.

The Slim Quick formulae are designed depending upon the requirement of every individual .the three different combinations are: Slim Quick Extreme, Original Slim Quick and Slim Quick Night. Though the formulae are highly recommended by the manufacturer yet the same was not approved by the FDA .Thus there are always chances that women consuming the same might suffer from some adverse effects. This entire fact is concealed by the manufacturer claiming the drug to be effective. Though the ingredients used for the manufacture of Slim Quick is known to have health benefit yet there is no substantial proof in this.

One of the basic ingredients of Slim Quick is caffeine which is known to increase heart rate thus leads to health issues. This is especially applicable for those having a history of heart ailment.

Like the caffeine there are other ingredients known to elevate the heart beat thus reducing our desire for food .The supplement is also known to reduce the water content in our body. Apart from past heart ailment this medicine is not recommended for individual with hypertension or patients using herbal or other kind of medications. As already discussed this drug is known to reduce the water content of our body .This condition is also referred to as diuretic condition. This property is known to deplete the essential vitamins and nutrition from our body.

The basic ingredients of Slim Quick are responsible to affect our health.

  • Dandelion Roots is one of the main ingredients and is known to interfere with the medications like antibiotics and lithium. Therefore individual undergoing any kind of medical session should be forbidden to consume Slim Quick. Since it might lead to mouth sores and allergy.
  • Pine bark (another key ingredient) is known to enhance the mental irritation and decrease the energy of our body.
  • Another ingredient Uva Ursi is known to cause nausea and vomiting since it is has huge concentration of tannin in it. The side effect intensifies if you accompany intense workout with an aim of decreasing your body weight.
  • The horsetail herb is known to be a potential threat since it is known to interfere with the normal performance of kidney, thus causing a disparity in balance between salt and water. If this continues for a prolong period of time the victim is likely to suffer from heart ailment .Moreover individuals undergoing treatment  for nicotine should not consume Slim Quick.
  • However the extract of yebra mate is known to be the worst in the list. Several researches have revealed that this herb is carcinogenic in nature. Therefore it is a potential contributor in respiratory, neck, digestive and lung cancer.
  • Finally, Slim Quick is strictly forbidden for pregnant ladies as clary sage another component of Slim Quick is known to deteriorate the physical condition of the would be mothers.

 

 

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Anatabloc Side Effects

English: Logo of the .

English: Logo of the . (Photo credit: Wikipedia)

Antabloc is a supplement sold in some health food stores as a treatment for chronic inflammation and joint pain. The primary ingredient in the supplement is antabine. Antabine is chemically similar to nicotine, but has a longer half life. Many anti-smoking medications are looking to start using antabine as an ingredient in their products.

Antabloc is in the per-clinical stages so there has not been many peer reviewed studies on the supplement. Mouse testing conducted on antabine, the main ingredient in Antabloc, showed no side effects of note. Rabbit testing on the other hand showed that rabbits who were given antabine had babies with low birth weights. Although there have not been any reports of side effects people who use Antabloc should be aware that the supplement could alter their mood or emotional state. The chemical make-up is so close to that nicotine that this side effect cannot be ruled out.

It should be understood that this supplement is not FDA approved, as a supplement the FDA usually won’t get involved unless there is proof of harm. This means that this supplement does not have to go through the rigorous testing that a medication would have to go through. Without clinical studies on human beings there will likely be side effects discovered over the next few years as the population uses the supplement more and more.

All medications and supplements pose risks to the human body. Without further studies it can be hard to know what the risks are when using Antabloc and if those risks are worth using the supplement. Cost is also a concern with Antabloc; it is an expensive supplement to buy. For those in chronic pain it may be worth risking unknown side effects to use the supplement for relief. Some people who are desperate may also try the supplement as one study showed that is slowed the progression of certain age related diseases that attack the mental capabilities of their victims. The use of this supplement is a big decision and it should only be considered if you are in a lot of pain and other traditional forms of  proven medications that are FDA approved do not work. Hopefully over the next few years the manufacturers of Anabloc will further test their supplement, get FDA approval as a drug, or at least give the general population access to their studies and not just medical doctors.

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Phendimetrazine Side Effects

English: 2D structure of anti-obesity drug phe...

English: 2D structure of anti-obesity drug phendimetrazine (Photo credit: Wikipedia)

People that are overweight can take the medicine Phendimetrazine. This product can help a person lose weight when combined with a healthy diet and an exercise regime. Calories still have to be monitored and controlled but this medication makes it easier to see weight loss results. These pills can only be prescribed by your physician.

These pills decrease the appetite when you take them. There’s a high risk of dependency on the medication so it cаn only be given to a patient for a short time. If it’s used too long the drug become ineffective for weight loss.

Side Effects

This drug can cause symptoms of tiredness so it’s not recommended that a person drive or operate machinery when on these pills. Any activity or work that required high levels of concentration may also be impacted if a person is on this medication. Some other Phendimetrazine include mental and physical addiction. A person that takes this drug may want to continue use evne after the effective period has worn off. The drug can therefore be quite addictive and a person may exceed the recommended dosage to get the feeling of the drug. Since the drug is addictive the administration of the drug needs to be monitored by a health care provider. Once a person stops using the drug, there can be withdrawal symptoms that are similar to the withdrawal symptoms of other drugs.

Other Side Effects

There can be side effects such as the inability to sleep, blurred vision or hyperactivity.  Phendimetrazine side effects tend to occur if a person takes too much of this drug. Some serious side effects can include a rapidly beating heart, allergic reactions or a desire to take this drug more often than prescribed.

Side Effects

  • Aggressive or outgoing behavior
  • Strange or abnormal behavior
  • Seeing things or other hallucinations
  • Restlessness or tiredness
  • High blood pressure
  • A heart rate that it rapid
  • Heart palpitations
  • Desire to take the drug all the time or dependency
  • The feeling that you need a higher dose
  • Rash or hives
  • Difficulty breathing or swallowing
  • Swelling

If you experience any Phendimetrazine side effects it’s important to see your doctor to discuss them. This  product can help you lose weight but it must be taken as prescribed. If you experience any serious side effects from the drug you should visit your local emergency ward to ensure you haven’t had a reaction to the drug or an overdose.

 

 

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