Generic Name: Alprazolam 2 mg
Alprazolam is a benzodiazepine used for the treatment of anxiety and panic disorder. It is white, rectangle, and with an imprint “G 372 2. Alprazolam works by balancing chemicals in the brain and is a medicine used to calm and sedate, however, causes severe withdrawal symptoms and may be addictive when misused.
It is available in a variety of dosage forms (short-acting tablets, long-acting tablets, oral solution, orally-dissolving tablets) and in less expensive generic forms.
RESPONSE AND EFFECTIVENESS
Immediate-release and orally disintegrating tablets – peak occurs 1 to 2 hours following administration.
Extended-release forms – consistent levels are reached within 5 to 11 hours.
Response and effectiveness vary between individuals (Asians are more sensitive to the effects of Alprazolam), weight (drug lasts longer in people with more body weight), in people who smoke, and with different formulations.
- It relieves anxiety and panic disorder and is effective at inducing calmness.
- Short-acting form is less likely to cause daytime sedation, when used to sleep at night.
In general, use of Alprazolam by elderly, children, and by people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects.
It is important to seek emergency help with these symptoms:
- Allergic Reaction – hives, difficulty breathing, swelling of face, lips, tongue, and throat.
- Serious Side Effects – depressed mood, suicidal or racing thoughts, increased energy, unusual risk taking behavior, confusion, agitation, hostility, hallucinations, uncontrolled muscle movements, tremors, seizures or convulsions, pounding heartbeats and chest fluttering.
- Overdose – extreme drowsiness, confusion, muscle weakness, light headedness, fainting, and loss of balance or coordination.
This is not a complete list of side effects and some other symptoms may occur. Less common side effects include: memory problems, anxiety in the morning, slurred speech, lack of balance and coordination, drowsiness, and feeling tired. Some side effects do not require medical attention as the body adjusts to taking the medication, so it is therefore important to talk with your doctor the benefits and unwanted effects or symptoms of this medicine.
- Mix the oral solution with liquids or semisolid food (such as water, applesauce, puddings), using only the calibrated dropper provided.
- Use dry hands to place orally-disintegrating tablets on the tongue and allow to dissolve slowly.
- Extended-release tablets should be taken in the morning, swallowed whole, and not crushed or chewed.
- Keep in a secure place, away from children and pets. Distribution of this medicine is also prohibited.
- Alprazolam is habit-forming. Misuse can cause addiction, overdose, or death. Keep in a secure place to avoid use and misuse by others.
The following side effects are more likely experienced by ages 18 to 60 years old, not taking any medication and having no other medical conditions:
- Low blood pressure, dizziness on standing (may increase the risk of falls), and heart palpitations.
- Stomach upset including constipation and nausea. Dry mouth, headache and a decrease in libido (sexual drive) are also common.
- Known to cause emotional and physical dependence (addiction).
- May impair reaction skills and affect a person’s ability to drive or operate machinery. Avoid alcohol.
- Smokers may have less of a response.
CAUTION AND PRECAUTIONS
- Avoid operating machinery, driving, or performing tasks that require mental alertness while taking this medicine.
- Avoid alcohol while taking this medicine. Alprazolam increases the effect of alcohol and may cause dangerous side effects.
- Withdrawal symptoms (blurred vision, insomnia, sweating, rarely seizures) may occur if long-term alprazolam is stopped abruptly; discontinue slowly on a doctor’s advice.
- Do not use if you have: allergy to alprazolam or similar medicine or any of its component, with acute narrow angle glaucoma, pregnant, planning to get pregnant or breastfeeding.
- Do not take with itraconazole (Sporanox) or ketoconazole (Nizoral). Always inform the doctor of any medicines you are currently taking or if you intend to undergo surgeries or operations.
It is important to discuss further with your doctor the benefits and side effects of this medication and what needs to be avoided while under medication. Inform the doctor if the medicine seems to stop working and if some side effects are bothersome or seemed unusual. Remember to always follow doctors’ advice and prescription labels.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
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